Dual-Stage Crosslinking of a Gel-Phase Bioink Improves Cell Viability and Homogeneity for 3D Bioprinting.

نویسندگان

  • Karen Dubbin
  • Yuki Hori
  • Kazuomori K Lewis
  • Sarah C Heilshorn
چکیده

Current bioinks for cell-based 3D bioprinting are not suitable for technology scale-up due to the challenges of cell sedimentation, cell membrane damage, and cell dehydration. A novel bioink hydrogel is presented with dual-stage crosslinking specifically designed to overcome these three major hurdles. This bioink enables the direct patterning of highly viable, multicell type constructs with long-term spatial fidelity.

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عنوان ژورنال:
  • Advanced healthcare materials

دوره 5 19  شماره 

صفحات  -

تاریخ انتشار 2016